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Evidence · Published 26 October 2026

Adding a hormonal IUD after endometrial ablation reduced later hysterectomies

In the 715-participant MIRA2 trial, hysterectomy within two years occurred in 4% of women receiving combined treatment and 10% receiving endometrial ablation alone.

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Independent women’s-health reporting on what changed, why it matters and what to watch next.

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Health & science

Evidence before excitement.

Research, medicine and technology—reported with the limits, source and unanswered questions intact.

Adding a hormonal IUD after endometrial ablation reduced later hysterectomies

In the 715-participant MIRA2 trial, hysterectomy within two years occurred in 4% of women receiving combined treatment and 10% receiving endometrial ablation alone.

Required U.S. mifepristone form made little difference to patient knowledge

Among 593 patients receiving routine counselling, adding the US Patient Agreement Form did not produce a clinically meaningful improvement in knowledge.

Vaginal CO₂ laser offered no added benefit over sham in breast-cancer survivors

Both groups improved while receiving first-line supportive care, but five laser sessions added no measurable benefit over sham treatment at 12 months.

Policy & access

The system shapes the outcome.

Health policy, regulation, care delivery and the decisions that determine who can access care.

FDA approves first generic once-weekly combined menopause patch

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Midi expands virtual care for UTIs, bacterial vaginosis and yeast infections

The new service combines acute appointments with follow-up when recurring symptoms need further assessment.

Allara raises $30M to expand integrated, insurance-covered women’s healthcare

The virtual-care company plans to expand clinical technology, partnerships and research across hormonal, metabolic and reproductive health.

From the archive

The women's health news archive starts in January 2025.

Historical news publications use the source or event date and are clearly marked as archive reporting.

Explore 20 archive news publications ↗

EndoSure gains a European CE mark—but its evidence questions are not settled

The non-invasive endometriosis test can be marketed in the EU, while US use remains research-only and independent clinical validation is still limited.

The endometriosis peptide ENDO-205 can now begin human testing

FDA clearance of an investigational application allows a planned Phase 1 study to proceed; it is not approval of the treatment, and no human efficacy data have been reported.

FDA approves the first generic low-dose estradiol vaginal insert

The generic version of Imvexxy adds another potential access route for painful sex associated with menopausal vulvar and vaginal atrophy.

WHO issues its first global guideline on infertility care

Forty recommendations address prevention, diagnosis, staged treatment, psychosocial support and the affordability of fertility care.